Septerna
SEPN · NASDAQ
$39.35+$2.97 (+8.16%)TodayMarket closed ·
Prev close $36.38
Who owns SEPN
Largest institutional holders, from their latest 13F filings
The 10 largest institutions hold 72.5% of SEPN’s shares.
- Third Rock Ventures, LLC22.8%
- RA Capital Management, LP12.2%
- Driehaus Capital Management, LLC9.8%
- Samsara BioCapital, LLC7.0%
- Next 6 largest institutions20.7%
- All other shareholders27.5%
| Holder | Shares | % of shares |
|---|---|---|
| Third Rock Ventures, LLC | 10.28M | 22.80% |
| RA Capital Management, LP | 5.50M | 12.21% |
| Driehaus Capital Management, LLC | 4.43M | 9.83% |
| Samsara BioCapital, LLC | 3.15M | 6.99% |
| Invus Public Equities Advisors, LLC | 1.90M | 4.21% |
| BlackRock Institutional Trust Company, N.A. | 1.72M | 3.82% |
| Goldman Sachs & Co. LLC | 1.72M | 3.81% |
| Goldman Sachs Asset Management, L.P. | 1.34M | 2.98% |
| Avoro Capital Advisors LLC | 1.34M | 2.97% |
| Janus Henderson Investors | 1.31M | 2.90% |
Largest mutual fund holders
| Holder | Shares | % of shares |
|---|---|---|
| Vanguard Total Stock Market Index Fund | 927.66K | 2.06% |
| PRIMECAP Odyssey Aggressive Growth Fund | 835.28K | 1.85% |
| iShares Russell 2000 ETF | 576.00K | 1.28% |
| Loomis Sayles Small Cap Growth Fund | 424.27K | 0.94% |
| Driehaus Small Cap Growth Fund | 417.86K | 0.93% |
Insider trades
Form 4 filings by officers, directors and large holders
Over the last 6 months, insiders sold $73.72M (18 trades) of SEPN on the open market, with no buys.
| Insider | Type | Shares | Value |
|---|---|---|---|
| Patni Rajiv | Award | 275.00K | — |
| Long Daniel D. | Option exercise | 3.33K | — |
| Long Daniel D. | Sale | 3.33K | $126.08K |
| Long Daniel D. | Option exercise | 3.33K | $9.20K |
| Third Rock Ventures V, L.P. | Sale | 141 | $7.20K |
| Third Rock Ventures V, L.P. | Sale | 147.06K | $7.39M |
| RA CAPITAL MANAGEMENT, L.P. | Sale | 746.50K | $31.73M |
| RA CAPITAL MANAGEMENT, L.P. | Sale | 746.50K | $31.73M |
| Bhatt Elizabeth | Option exercise | 6.32K | — |
| Bhatt Elizabeth | Option exercise | 18.68K | — |
Short interest
Settled Sep 30, 2026
- Shares short
- 3.10M
- Days to cover
- 8.80
- % of shares outstanding
- 6.87%
- Average daily volume
- 351.89K
- Change since last report
- +7.0%
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