TRex Bio

TRex Bio, Inc. is a US-based company operating in industry. The company is headquartered in South San Francisco, California. The company went IPO on 2026-10-09. TRex Bio, Inc is a clinical-stage biopharmaceutical company focused on tissue Treg biology for the discovery and development of immunoregulatory medicines designed to restore immune balance and promote tissue repair to address unmet needs of patients with autoimmune and inflammatory diseases. The firm's Deep Biology platform decodes Treg functionality in human tissue, mapping key drivers of immune dysregulation and uncovering novel targets and insights that inform drug discovery and translational efforts. This platform has generated multiple therapeutic development candidates across its wholly owned pipeline and through collaborations with pharma partners. Its product candidate, TRB-061, is an investigational tumor necrosis factor receptor 2 (TNFR2) agonist designed to expand and activate Tregs in inflamed tissues. TRB-071 is an investigational CD30 agonist designed to both augment tissue Tregs and block an immune system inflammatory pathway.